Multiple ethernet ports/Linux/Connection error

Hello

I have a strange teamviewer conneciton problem. 
The machine is running Linux. 
It has one interface wifi (wlp2s0) and one internal connection (enp3s0) hard configured to 192.168.1.2

The wifi get its address via DHCP. 
wlp2s0 10.0.0.176 Bcast 10.0.0.255 Mask 255.255.255.0
enp3s0 192.168.1.2 Bcast 192.168.1.255 Mark 255.255.255.0

The routing tables look like this:
default via 10.0.0.99 dev wlp2s0 
10.0.0.0/24 dev wlp2s0 proto kernel scope link src 10.0.0.176
169.254.0.0/16 dev enp3s0 scope link metric 1000
192.168.1.0/24 dev enp3s0 scope link src 192.168.1.2

Now the problem is - as soon as enp3s0 is activated there is no teamviewer connection any more. I am totally puzzles how this happens. With different PCs it working without any problems...

Anyone can help?
Thank you!