Host and Client PC Win7 - Client freezes fully while downloading some files

Hi folks,

Im installing Autodesk software in a well known enviroment and never got an issue the past years.

Since this week, I got a full freeze on all clients, while downloading some files. Only a hard reset will reboot the Client.

Im the Teamviewer Host and disabled UDP and on the Client all Antivirus Software, but still a full freeze.

May I ask for some input? Any ideas would be very appreciated. Thanks a lot!